Analyzing Patterns of Drug Use in Clinical Notes for Patient Safety
نویسندگان
چکیده
Doctors prescribe drugs for indications that are not FDA approved. Research indicates that 21% of prescriptions filled are for off-label indications. Of those, more than 73% lack supporting scientific evidence. Traditional drug safety alerts may not cover usages that are not FDA approved. Therefore, analyzing patterns of off-label drug usage in the clinical setting is an important step toward reducing the incidence of adverse events and for improving patient safety. We applied term extraction tools on the clinical notes of a million patients to compile a database of statistically significant patterns of drug use. We validated some of the usage patterns learned from the data against sources of known on-label and off-label use. Given our ability to quantify adverse event risks using the clinical notes, this will enable us to address patient safety because we can now rank-order off-label drug use and prioritize the search for their adverse event profiles.
منابع مشابه
Using Temporal Patterns in Medical Records to Discern Adverse Drug Events from Indications
Researchers estimate that electronic health record systems record roughly 2-million ambulatory adverse drug events and that patients suffer from adverse drug events in roughly 30% of hospital stays. Some have used structured databases of patient medical records and health insurance claims recently-going beyond the current paradigm of using spontaneous reporting systems like AERS-to detect drug-...
متن کاملسیستم اطلاعات ایمنی بیمار: اهداف، ساختار و وظایف
Patient safety is the key element of quality in healthcare. Ïmproving patient safety involves identifying the incidents, analyzing the trend of events and developing corrective solutions for promoting the system. Health care organizations can not judge the safety of the care without data and information related to patient safety. Therefore, patient safety information system (PSÏS( is used in ...
متن کاملPotential Drug-drug Interactions in Post-CCU of a Teaching Hospital
Drug-drug interactions (DDIs) can lead to increased toxicity or reduction in therapeutic efficacy. This study was designed to assess the incidence of potential drug interactions (PDI) and rank their clinical value in post coronary care unit (Post-CCU) of a teaching hospital in Tehran, Iran.In this prospective study, three pharmacists with supervision of a clinical pharmacist actively gathered n...
متن کاملPotential Drug-drug Interactions in Post-CCU of a Teaching Hospital
Drug-drug interactions (DDIs) can lead to increased toxicity or reduction in therapeutic efficacy. This study was designed to assess the incidence of potential drug interactions (PDI) and rank their clinical value in post coronary care unit (Post-CCU) of a teaching hospital in Tehran, Iran.In this prospective study, three pharmacists with supervision of a clinical pharmacist actively gathered n...
متن کاملAn Inquiry into the Patient Safety Management Patterns: A Review Study
Background and aims: Patient safety, as one of the main components of the health care quality, impliesavoiding any injury and damage to the patient when providing health care services. In other words,patient safety means his or her safety against any adverse and harmful event when receiving health careservices. Based on the above-mention explanations, the present study was con...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 2012 شماره
صفحات -
تاریخ انتشار 2012